In a thrilling AFC showdown at Highmark Stadium on November 2, 2025, the Buffalo Bills defeated the Kansas City Chiefs 28-21. This was the Bills’ fifth straight regular-season win over the Chiefs. Josh Allen had an amazing game, rushing for two touchdowns and throwing for another. The Bills showed their dominance with a balanced offensive and defensive effort.
Buffalo’s defense was relentless, sacking Chiefs quarterback Patrick Mahomes three times and throwing him off his game all game long. Even though Mahomes tried to make a late comeback, his last passes were stopped, and the Chiefs lost in the last few seconds.
The Chiefs are now 5-4 and two games behind the Denver Broncos, who are in first place in the division. This loss puts Kansas City in third place in the AFC West. The loss also puts the Chiefs out of the playoff picture for now, which is unusual for the team under Mahomes’ leadership. Since becoming the starter, he has led the team to the AFC Championship Game every year.
Running back James Cook, who ran for 114 yards, and tight end Dalton Kincaid, who caught 101 yards and a touchdown, were two of the Bills’ most important players. Buffalo’s record has improved to 6-2, which puts them one game behind the New England Patriots, who are in first place in the AFC East.
The AFC West is getting more competitive as the Broncos (7-2) and Los Angeles Chargers (6-3) also have good records. This sets the stage for important divisional games, including two key Chiefs vs. Broncos games.
As the season goes on, the Chiefs have a long way to go to get back into the race, and they can’t afford to make any mistakes in the tough AFC.